Tiny chip can REGROW damaged organs in MAJOR medical breakthrough

  • Tiny chip can REGROW damaged organs in MAJOR medical breakthrough

Tiny chip can REGROW damaged organs in MAJOR medical breakthrough

A small electric current fires DNA into skin cells to convert them into natural cell building blocks which helps to fix the damaged areas such as arteries and even organs like the heart.

Published in Nature Nanotechnology, the new study's First Author Daniel Gallego-Perez of Ohio State showed that the method functioned with up to 98% efficiency. "You simply touch the chip to the wounded area, then remove it", said Chandan Sen, director, center for regenerative medicine and cell-based therapies, The Ohio State University Wexner Medical Center.

The technology, referred to as Tissue Nanotransfection (TNT), injects genetic code into skin cells, transforming those skin cells into other types of cells essential for treating diseased conditions.

Researchers have developed a tiny chip that, when applied to an affected area, can regenerate and fix failing body functions by turning skin cells into other types of healing cells. By doing so, the device turn the skin cells into other cell types which are required to treat the patient's disease.

Says Sen: "By using our novel nanochip technology, injured or compromised organs can be replaced".

The breakthrough technology marks the first time that cells have been reprogrammed in a live body.

The device has not yet been tested in humans, but it has proved successful with mice and pigs.

"The concept is very simple", Lee said.

In one experiment, a badly damaged mouse leg was saved by the technology creating new blood vessels in tissue that had previously been lacking blood flow.

In a series of lab tests, researchers from Ohio State University Wexner Medical Center applied the chip to the injured legs of mice that vascular scans showed had little to no blood flow. "As a matter of fact, we were even surprised how it worked so well". So far, there are no known side effects from using TNT, and the treatment takes less than a second. For a long time researchers have tried to come up with a mechanism that could treat and even fix brain injuries. Actually, the Researchers managed to grow brain cells on the skin surface of a mouse, harvest them and then inject them into the injured brain of the mouse. "So this is the beginning, more to come".

TNT does not require any laboratory-based procedures and may be implemented at the point of care.

Dr. Sen said he hopes to begin trials within a year.